An Unexpected C‐S Bond Transformation with High Chemoselectivity for the Synthesis of Aryl‐Benzyl Sulfones. Issue 33 (1st September 2021)

• Record Type: Journal Article
• Authors: Liu, Teng; Shen, Xianfu; Liu, Zining; Shi, Rong; Wei, Wen; Xu, Yanli; Cheng, Feixiang
• Is Part Of: ChemistrySelect. Volume 6:Issue 33(2021)
• Page Start: 8685
• Page End: 8688
• Publication Date: 2021-09-01
• Subjects: Aryl-benzyl sulfones -- Aryl-alkyl sulfones -- C−S bond formation -- Dibenzyl phosphite -- Metal-free; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.202102247
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: In this report, an unexpected C−S bond transformation involving a high chemoselectivity between sulfonylhydrazides and dibenzyl phosphite catalyzed by NaI under mild conditions has been developed. This alternative protocol could provide a metal‐free route to access a diverse aryl‐benzyl sulfones in good to excellent yields. Abstract : In this report, an unexpected C−S bond transformation involving a high chemoselectivity between sulfonylhydrazides and dibenzyl phosphite catalyzed by NaI under mild conditions has been developed. This alternative protocol could provide a metal‐free route to access a diverse aryl‐benzyl sulfones in good to excellent yields and with high chemoselectivity.