Increased ambulatory arterial stiffness index correlated with monocyte chemoattractant protein-1 in prehypertensives. (12th October 2011)

• Record Type: Journal Article
• Authors: Liu, Zhendong; Lu, Fanghong; Dong, Yuanli; Wang, Shujian; Zhao, Yingxin; Sun, Shangwen; Pan, Hui
• Is Part Of: Heart. Volume 97(2011)Supplement 3
• Page Start: A235
• Page End: A235
• Publication Date: 2011-10-12
• Subjects: Heart -- Diseases -- Treatment -- Periodicals; Cardiology -- Periodicals; 616.12
• DOI: 10.1136/heartjnl-2011-300867.692
• Languages: English
• ISSNs: 1355-6037

Abstract

Abstract : Objective: To investigate increased ambulatory arterial stiffness index correlated with plasma level and expression of monocyte chemoattractant protein-1. Methods: One hundred and eight subjects with prehypertension and 101 optimal normotensive subjects were eligible enrolled. Non-invasive ambulatory blood pressure monitoring was performed using automatic devices (TM-2421 and TM-2430; A&D, Tokyo, Japan) and ambulatory arterial stiffness index was calculated in all participants. Monocyte chemoattractant protein-1 expression was conducted by quantitative real-time reverse transcription-PCR (RT-PCR). Results: Ambulatory arterial stiffness index was 0.48±0.10% in prehypertensives, higher than that in optimism normotensives (t value=10.689, P-1 in prehypertensives.