Proteins of the fruit pulp of Acca sellowiana have antimicrobial activity directed against the bacterial membranes. Issue 17 (19th August 2021)

• Record Type: Journal Article
• Authors: Di Napoli, Michela; Maresca, Viviana; Sorbo, Sergio; Varcamonti, Mario; Basile, Adriana; Zanfardino, Anna
• Is Part Of: Natural product research. Volume 35:Issue 17(2021)
• Page Start: 2942
• Page End: 2946
• Publication Date: 2021-08-19
• Subjects: Antimicrobial activity -- pulp fraction -- protein extracts -- Acca sellowiana; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1675655
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Acca sellowiana is an evergreen plant that produces edible fruit whit high nutritional properties, and also contains clinically relevant bioactive compounds, including polyphenols and essential oils. Numerous biological activities were demonstrated for A. sellowiana fruits: antifungal and antitumoral and anti-oxidant. It was also showed a strong antibacterial activity against Gram-positive and Gram-negative bacteria. Fruit are generally considered recalcitrant plant tissues for the difficulty to obtain high quality protein due to a low protein content and the presence of interfering substances. For this reason, the objective of the present work was obtain high quantity of protein extract, to determine the location in the fruit of the molecules responsible for the antibacterial activity, separate them according to molecular weight, test their thermo resistance, study the timing of action, isolate the protein fraction having activity and hypothesise a mechanism of action directed against bacterial membranes. Abstract : UF0001