2, 2, 6, 6‐Tetramethylpiperidinyloxyl (TEMPO) Radical Mediated Electro‐Oxidation Reactions: A Review. Issue 30 (16th August 2021)

• Record Type: Journal Article
• Authors: Prakash, Nishitha; Rajeev, Rijo; John, Anjali; Vijayan, Ajesh; George, Louis; Varghese, Anitha
• Is Part Of: ChemistrySelect. Volume 6:Issue 30(2021)
• Page Start: 7691
• Page End: 7710
• Publication Date: 2021-08-16
• Subjects: Aminoxyl radical -- Electrocatalysts -- Electrochemistry -- Electro-oxidation reactions -- TEMPO; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.202102346
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: Over the last few decades, the interest in green and sustainable chemistry has led to the development of different synthetic methodologies which utilize clean reagents. In that direction, the electro‐oxidation reactions are considered as one of the most interesting and promising methods. This is predominantly due to their environmentally benign nature, as oxidation can be achieved without the need for commonly used oxidizing agents. 2, 2, 6, 6‐Tetramethylpiperidinyloxyl radical commonly known as TEMPO is a stable aminoxyl radical utilized for the oxidation of various classes of alcohols to carbonyl compounds by using cyclic voltammetry. The present review focuses on the various electrochemical reactions utilizing TEMPO as a mediator such as the oxidative conversion of alcohols, carbohydrates, amines, sulphur‐containing compounds, and alkenes in both laboratory as well as industrial scales and covers literature from 1950 till present date. The properties, reactivity, and yield percentages of these reactions would provide a basis for better electrocatalyst design in future studies involving TEMPO and its derivatives as mediators. Abstract : 2, 2, 6, 6‐Tetramethylpiperidinyloxyl (TEMPO) is an organic nitroxyl which is widely used as a catalyst in electrochemical redox reactions. The authors have extensively reviewed the past, present, and future aspects of TEMPO mediated electrocatalytic oxidation of various substrates such as alcohols, carbohydrates, amines, alkenes, sulphur‐containing compounds. Additionally, TEMPO derivatives and TEMPO combined with co‐catalysts have also been reviewed.