A rare case of childhood mucous membrane pemphigoid involving the oral and genital mucosa. Issue 4 (11th May 2021)

• Record Type: Journal Article
• Authors: Rodriguez Baisi, Katinna; Wentworth, Ashley; Chattha, Asma J.; DiCaudo, David J.; Mangold, Aaron; Nelson, Steven A.; Siegfried, Elaine; Wieland, Carilyn N.; Tollefson, Megha
• Is Part Of: Pediatric dermatology. Volume 38:Issue 4(2021)
• Page Start: 904
• Page End: 907
• Publication Date: 2021-05-11
• Subjects: immunobullous disease -- mucous membrane disorders; Pediatric dermatology -- Periodicals; Children -- Diseases -- Periodicals; 618.925
• DOI: 10.1111/pde.14627
• Languages: English
• ISSNs: 0736-8046

Abstract

Abstract: Mucous membrane pemphigoid (MMP) is a rare chronic immunobullous disease that involves the mucous membranes and may result in significant scarring and complications if diagnosis is delayed. MMP typically occurs in elderly patients, with very few cases reported in children. Here, we present a 12‐year‐old female patient with childhood‐onset oral and genital MMP, clinically suspected to be lichen sclerosus, but eventually diagnosed as MMP after multiple supportive biopsies and confirmatory direct immunofluorescence. Although treatment was challenging, the combined use of systemic corticosteroids, dapsone, and mycophenolate mofetil was ultimately successful in achieving disease control.