Brønsted acid-catalyzed chlorination of aromatic carboxylic acids. (30th August 2021)

• Record Type: Journal Article
• Authors: Yu, Zhiqun; Yao, Hongmiao; Xu, Qilin; Liu, Jiming; Le, Xingmao; Ren, Minna
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 196:Number 8(2021)
• Page Start: 685
• Page End: 689
• Publication Date: 2021-08-30
• Subjects: Brønsted acid-catalyzed -- aromatic carboxylic acid -- thionyl chloride -- chlorination; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2021.1903008
• Languages: English
• ISSNs: 1042-6507

Abstract

Abstract: The chlorination of aromatic carboxylic acids with SOCl2 has been effectively performed by reacting with a Brønsted acid as the catalyst. Based on this discovery, an efficient catalytic method that is cheaper than traditional catalytic methods was developed. 20 substrates were chlorinated offering excellent yields in a short reaction time. And the SOCl2 /Brønsted acid system has been used in a larger scale preparative reaction. A dual activation mechanism was proposed to prove the irreplaceable system of SOCl2 /Brønsted acid. Graphical Abstract: UF0001