A lipidomic view of SARS-CoV-2. Issue 8 (27th August 2021)

• Record Type: Journal Article
• Authors: Ebrahimi, Kourosh H.; McCullagh, James S.O.
• Is Part Of: Bioscience reports. Volume 41:Issue 8(2021)
• Publication Date: 2021-08-27
• Subjects: COVID-19 -- HDL -- Immune system -- lipids -- Metabolomics -- SARS-CoV-2; Molecular biology -- Periodicals; Cytology -- Periodicals; 572.8
• DOI: 10.1042/BSR20210953
• Languages: English
• ISSNs: 0144-8463

Abstract

Abstract: The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which started in late 2019, has caused huge social and economic losses. A growing number of investigators are focusing on understanding the interaction of SARS-CoV-2 with host cellular processes to find therapeutic approaches. New data suggest that lipid metabolism may play a significant role in regulating the response of immune cells like macrophages to viral infection, thereby affecting the outcome of the disease. Therefore, understanding the role of lipid metabolism could help develop new therapeutic approaches to mitigate the social and economic cost of coronavirus disease 2019 (COVID-19).