An immunohistological study of spontaneous regression of condylomata acuminata. Issue 2 (April 1990)

• Record Type: Journal Article
• Authors: Bishop, P E; McMillan, A; Fletcher, S
• Is Part Of: Sexually transmitted infections. Volume 66:Issue 2(1990)
• Page Start: 79
• Page End: 81
• Publication Date: 1990-04
• Subjects: Sexually transmitted diseases -- Periodicals; HIV infections -- Periodicals; 616.951005
• DOI: 10.1136/sti.66.2.79
• Languages: English
• ISSNs: 1368-4973

Abstract

Abstract : An immunohistological study of four men whose perianal warts were undergoing spontaneous regression was undertaken, and the results compared with those obtained from non-regressing condylomata from six men. CD4+ and CD8+ cells were noted in the stroma of each wart, but there was no clear difference in the density of the infiltrate between regressing and non-regressing warts. Natural killer cells (CD16+ and CD57+) were only noted in the stroma and epidermis of regressing warts. Possible immunological mechanisms of regression of condylomata acuminata are discussed.