Design and mechanism of photocurrent-modulated graphene field-effect transistor for ultra-sensitive detection of DNA hybridization. (September 2021)

• Record Type: Journal Article
• Authors: Sun, Yang; Xu, Shicai; Zhu, Tiying; Lu, Jiajun; Chen, Shuo; Liu, Maomao; Wang, Guangcan; Man, Baoyuan; Li, Huamin; Yang, Cheng
• Is Part Of: Carbon. Volume 182(2021)
• Page Start: 167
• Page End: 174
• Publication Date: 2021-09
• Subjects: Photocurrent -- Field-effect transistor -- Graphene -- DNA hybridization -- Biosensor; Carbon -- Periodicals; Carbone -- Périodiques; Koolstof; Toepassingen; Electronic journals; 546.681
• DOI: 10.1016/j.carbon.2021.06.003
• Languages: English
• ISSNs: 0008-6223

Abstract

Abstract: Field-effect transistors (FET) using low-dimensional materials has attracted attention for detection of DNA hybridization. Here, we proposed a photocurrent-modulated FET sensor, where the I p h o t o c u r r e n t ( g a t e ) + I p h o t o c u r r e n t ( D N A ) dramatically enhance the response signal, I c u r r e n t, compared to a traditional FET sensor. The proposed sensor successfully detects DNA signals with a limit of detection (LOD) down to attomolar concentrations that is nearly 100x lower than a traditional FET sensor. The sensing mechanism is postulated and discussed. The results suggest that photo-coupled modulation opens new avenues for further development of the FET in biosensing applications. Graphical abstract: Image 1