Acute limb ischemia with concomitant splenic and renal infarcts: Thromboembolic events revealing COVID-19. (August 2021)

• Record Type: Journal Article
• Authors: Berrichi, Samia; Bouayed, Zakaria; Berrajaa, Sara; Mezzeoui, Sanae EL.; Moujahid, Amal; Nasri, Siham; Bkiyar, Houssam; Skiker, Imane; Housni, Brahim
• Is Part Of: Annals of medicine and surgery. Volume 68(2021)
• Publication Date: 2021-08
• Subjects: COVID-19 -- Thromboembolic -- Limb ischemia; Surgery -- Periodicals; Medicine -- Periodicals; General Surgery -- Periodicals; Education, Medical -- Periodicals; Periodicals; 617
• DOI: 10.1016/j.amsu.2021.102646
• Languages: English
• ISSNs: 2049-0801

Abstract

Abstract: Introduction: Since December 2019, the coronavirus 19 (COVID-19) pandemic continues to spread worldwide and has caused millions of deaths. Although the main manifestation of the disease is acute respiratory distress syndrome, hypercoagulability resulting from hypoxemia leads to venous thromboembolism and arterial thrombosis, which have a fatal prognosis for COVID-19. Case report management: We report the case of patient admitted to our unit for management of a concomitant limb ischemia, splenic and renal infarcts associated to a COVID-19 infection with favorable outcomes after thrombectomy and therapeutic doses of heparin. Conclusion: Systemic procoagulant manifestations related to a COVID-19 infection is a newly described phenomenon responsible of cardiovascular and neurological disorders. Highlights: COVID-19 is a complex and multi-phased disease. The occurrence of arterial and venous thromboembolic events has been described throughout literature and linked to poor prognosis. Our case report demonstrates the likelihood of developing an arterial thrombosis even in the absence of cardiovascular comorbidities. Thromboembolic involvement during COVID-19 should be considered, and a deeper understanding of the pathophysiology is needed for optimal and management.