Design and Engineering of Amyloid Aggregation‐Prone Fragments and Their Antimicrobial Conjugates with Multi‐Target Functionality (Adv. Funct. Mater. 32/2021). (10th August 2021)

• Record Type: Journal Article
• Authors: Zhang, Yanxian; Tang, Yijing; Liu, Yonglan; Zhang, Dong; Zheng, Jie
• Is Part Of: Advanced functional materials. Volume 31:Number 32(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-08-10
• Subjects: Alzheimer disease -- amyloid proteins -- antimicrobial activity -- protein aggregation -- type 2 diabetes; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.202170236
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : Amyloid Aggregation In article number 2102978, Jie Zheng and co‐workers provide a new "kill two birds with one stone" model to not only reconcile with both the "amyloid cascade hypothesis" and "microbial infection hypothesis", but also reveal the functional and structural correlations between antimicrobial peptides and amyloid proteins with their built‐in bacterial killing and amyloid inhibition functions.