1272 Survival and Neurodevelopmental Outcome of Preterm Infants with a Gestational Age of 22 to 26 Weeks in a Regional Centre. (October 2012)

• Record Type: Journal Article
• Authors: Kutz, P; Supcun-Ritzler, S; Roll, C
• Is Part Of: Archives of disease in childhood. Volume 97(2012)Supplement 2
• Page Start: A363
• Page End: A363
• Publication Date: 2012-10
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/archdischild-2012-302724.1272
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Background and Aims: Counselling parents of extremely preterm infants requires knowledge on results of large population-based cohorts and contemporaneous local data. Methods: We assessed the outcome of all live-born infants 2006 to 2009 with a gestational of 22 to 26 weeks (outborns admitted to neonatal care and all inborns). At a corrected age of 24 months infants underwent Bayley Scales of Infant and Development II testing, clinical and neurological examinations. Results: There were 105 infants < 27 weeks born alive, with a median birth weight of 675 g (range 300–1300 g), of whom 23 (22%) died before discharge; (≤22 weeks 9/10; 23 weeks 9/18; 24 weeks: 3/22; 25 weeks 1/22; 26 weeks: 1/33). Two infants died after discharge. Complete follow-up data are available in 74 (93%) of the 80 survivors. The median MDI score was 94; >84 in 44 (59%), 84–70 in 20 (27%), and < 70 in 10 (14%) infants. The median PDI score was 98; >84 in 53 (72%), 84–70 in 12 (16%), and < 70 in 9 (12%) infants. None of the children were blind or deaf, 14 had glasses, 5 required hearing aids. Overall, neurodevelopment was classified as normal in 45 of 74 (61%) infants (22 weeks: 0/1; 23 weeks: 1/7; 24 weeks: 10/17; 25 weeks: 12/19; 26 weeks: 22/30). Conclusions: The rates of overall survival (76%) and normal neurological development among survivors (61%) were similar to contemporaneous data from for Sweden (70%) and the Stockholm area (65%), respectively.