Evaluation of Transfusion Pyrexia: A Review of Differential Diagnosis and Management. (15th October 2012)

• Record Type: Journal Article
• Authors: Arewa, Oladimeji P.
• Other Names: Carulli G. Academic Editor.; Pekrun A. Academic Editor.; Wachowicz B. Academic Editor.; Will A. M. Academic Editor.
• Is Part Of: ISRN hematology. Volume 2012(2012)
• Publication Date: 2012-10-15
• Subjects: Hematology -- Periodicals; Hematologic Diseases; Hematology; Hematology; Electronic journals; Periodical; Periodicals; Fulltext; Internet Resources; Periodicals; 616.15
• DOI: 10.5402/2012/524040
• Languages: English
• ISSNs: 2090-441X

Abstract

Abstract : Background/purpose . Transfusion pyrexia (fever) is an important clinical sign/symptom occurring either as an isolated event or as part of a constellation of signs and symptoms in relation to blood transfusion. It is an important cause of morbidity and may be an important sign of life-threatening complications of blood transfusion. Pyrexia is often a reason for the discontinuation of a blood transfusion episode, and adequate evaluation remains a challenge for clinicians. The decision to stop a blood transfusion episode on account of fever is often a difficult one. This paper reviews the differential diagnosis of transfusion pyrexia (TP), the pathogenesis as well as current management measures. Study selection and data source . Literature sources include medical texts, journals, dissertations, and internet-based electronic materials Results and conclusion . Adequate evaluation of pyrexia accompanying blood transfusion remains a challenge for clinicians. An algorithm to assist the clinician in the evaluation of fever occurring in a blood transfusion recipient is developed and presented. Continuous medical education is necessary for clinicians towards improved patient care in transfusion medicine.