Chemical Entity Recognition and Resolution to ChEBI. (15th February 2012)

• Record Type: Journal Article
• Authors: Grego, Tiago; Pesquita, Catia; Bastos, Hugo P.; Couto, Francisco M.
• Other Names: Aoki-Kinoshita K. F. Academic Editor.; Safran M. Academic Editor.
• Is Part Of: ISRN bioinformatics. Volume 2012(2012)
• Publication Date: 2012-02-15
• Subjects: Bioinformatics -- Periodicals; Computational biology -- Periodicals; Medical informatics -- Periodicals; Computational Biology; Medical Informatics; Bioinformatics; Computational biology; Medical informatics; Periodicals; Periodicals; 570.285
• DOI: 10.5402/2012/619427
• Languages: English
• ISSNs: 2090-7338

Abstract

Abstract : Chemical entities are ubiquitous through the biomedical literature and the development of text-mining systems that can efficiently identify those entities are required. Due to the lack of available corpora and data resources, the community has focused its efforts in the development of gene and protein named entity recognition systems, but with the release of ChEBI and the availability of an annotated corpus, this task can be addressed. We developed a machine-learning-based method for chemical entity recognition and a lexical-similarity-based method for chemical entity resolution and compared them with Whatizit, a popular-dictionary-based method. Our methods outperformed the dictionary-based method in all tasks, yielding an improvement in F -measure of 20% for the entity recognition task, 2–5% for the entity-resolution task, and 15% for combined entity recognition and resolution tasks.