Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS. (28th July 2021)

• Record Type: Journal Article
• Authors: Dong, Yaqian; Jia, Guoxiang; Hu, Jingwen; Liu, Hui; Wu, Tingting; Yang, Shenshen; Li, Yubo; Cai, Ting
• Other Names: Nikolova Damyanova Boryana M. Academic Editor.
• Is Part Of: Journal of analytical methods in chemistry. Volume 2021(2021)
• Publication Date: 2021-07-28
• Subjects: Chemistry, Analytic -- Periodicals; Chemistry, Analytic -- Technique -- Periodicals; 543.05
• DOI: 10.1155/2021/9915027
• Languages: English
• ISSNs: 2090-8865

Abstract

Abstract : This study is based on UHPLC-Q-TOF/MS and fragment ions to achieve classification and identification of alkaloids and flavonoids in Sophora flavescens . By reviewing the available and relevant literature, the mass fragmentation rules of alkaloids and flavonoids were summarized. 0.1% formic acid water (A) and acetonitrile (B) were used as mobile phases. 37 chemical constituents were identified, including 13 alkaloids and 24 flavonoids. This research method offers a complete strategy based on the fragmentation information of characteristic fragment ions and neutral loss obtained by MS/MS to characterize the chemical composition of Sophora flavescens .