Alkali-modified heterogeneous Pd-catalyzed synthesis of acids, amides and esters from aryl halides using formic acid as the CO precursor. Issue 43 (5th August 2021)

• Record Type: Journal Article
• Authors: Oseghale, Charles O.; Onisuru, Oluwatayo Racheal; Fapojuwo, Dele Peter; Mogudi, Batsile M.; Molokoane, Pule Petrus; Maqunga, Nomathamsanqa Prudence; Meijboom, Reinout
• Is Part Of: RSC advances. Volume 11:Issue 43(2021)
• Page Start: 26937
• Page End: 26948
• Publication Date: 2021-08-05
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d1ra05177f
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : To establish an environmentally friendly green chemical process, we minimized and resolved a significant proportion of waste and hazards associated with conventional organic acids and molecular gases, such as carbon monoxide (CO). Abstract : To establish an environmentally friendly green chemical process, we minimized and resolved a significant proportion of waste and hazards associated with conventional organic acids and molecular gases, such as carbon monoxide (CO). Herein, we report a facile and milder reaction procedure, using low temperatures/pressures and shorter reaction time for the carboxyl- and carbonylation of diverse arrays of aryl halides over a newly developed cationic Lewis-acid promoted Pd/Co3 O4 catalyst. Furthermore, the reaction proceeded in the absence of acid co-catalysts, and anhydrides for CO release. Catalyst reusability was achieved via scalable, safer, and practical reactions that provided moderate to high yields, paving the way for developing a novel environmentally benign method for synthesizing carboxylic acids, amides, and esters.