Percutaneous stent-in-stent placement with large cell-type stents for malignant hilar biliary obstruction. (December 2021)

• Record Type: Journal Article
• Authors: Kim, Gun Ha; Gwon, Dong Il; Ko, Gi-Young; Kim, Jin Hyoung; Kim, Jong Woo; Chu, Hee Ho; Yoon, Hyun-Ki; Sung, Kyu-Bo
• Is Part Of: Acta radiologica. Volume 62:Number 12(2021)
• Page Start: 1625
• Page End: 1631
• Publication Date: 2021-12
• Subjects: Malignant biliary obstruction -- percutaneous biliary stent -- stent-in-stent; Radiology, Medical -- Periodicals; Radiography, Medical -- Periodicals; Radiotherapy -- Periodicals; 616.0757
• DOI: 10.1177/0284185120978512
• Languages: English
• ISSNs: 0284-1851

Abstract

Background: To overcome the technical difficulty of bilateral stent-in-stent placement, large cell-type biliary stents have been developed. However, most of the studies using large cell-type stents were conducted with endoscopic method. Purpose: To evaluate the efficacy and safety of percutaneous stent placement with a stent-in-stent method using large cell-type stents in patients with malignant hilar biliary obstruction. Material and Methods: From December 2015 and October 2018, 51 patients with malignant hilar biliary obstruction were retrospectively studied. All of the patients underwent bilateral (n=46) or unilateral (n=5) stenting in a T, Y, or X configuration with a stent-in-stent method using large cell-type stents. Technical success, complications, successful internal drainage, stent patency, and patient survival were analyzed. Results: A total of 118 stents were successfully placed in 51 patients (100.0%). Three patients had minor complications with self-limiting hemobilia. Major complications were not observed in any patient. Successful internal drainage was achieved in 45 patients (88.2%). Clinical follow-up information until death or the end of the study was available for 50 of 51 patients. The median patient survival was 285.5 days (95% confidence interval [CI] 197–374). Stent dysfunction occurred in 16 patients (35.6%) due to tumor ingrowth (n=9) or tumor ingrowth combined with biliary sludge (n=7) among the patients who achieved successful internal drainage. Median stent patency was 179 days (95% CI 104–271). Conclusion: Percutaneous stent-in-stent placement with large cell-type stents is technically feasible and safe, and can be an effective technique in patients with malignant hilar biliary obstruction.