Carpal, cubital or tarsal tunnel syndrome after SARS-CoV-2 infection: A causal link?. (August 2021)

• Record Type: Journal Article
• Authors: Roncati, Luca; Gianotti, Greta; Gravina, Davide; Attolini, Giovanna; Zanelli, Giuliana; Rosa, Norman Della; Adani, Roberto
• Is Part Of: Medical hypotheses. Volume 153(2021)
• Publication Date: 2021-08
• Subjects: Coronavirus disease 2019 (COVID-19) -- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) -- Carpal tunnel syndrome -- Cubital tunnel syndrome -- Tarsal tunnel syndrome -- Histopathology; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Medicine; Periodicals; 610
• DOI: 10.1016/j.mehy.2021.110638
• Languages: English
• ISSNs: 0306-9877

Abstract

Abstract: COVID-19 is a complex disease with many clinicopathological issues, including respiratory, gastrointestinal, neurological, renal, cutaneous, and coagulative ones; in addition, reactive arthritis has been reported by different authors. Here, we hypothesize that a peripheral microangiopathy involving nerve supply, a viral demyelination, or an immune-mediated irritating antigenic stimulus on synovial sheaths after SARS-CoV-2 infection may all induce a carpal, cubital or tarsal tunnel syndrome of variable entity in genetically predisposed subjects associated with myxoid nerve degeneration.