Dramatic decline in new HIV diagnoses in persons born in France in a large nationwide HIV cohort. (July 2021)

• Record Type: Journal Article
• Authors: Le Guillou, A.; Cabie, A.; Delpierre, C.; Pugliese, P.; Jacomet, C.; Hentzien, M.; Duvivier, C.; Zaegel-Faucher, O.; Cotte, L.; Raffi, F.; Bani-Sadr, F.
• Is Part Of: Public health. Volume 196(2021)
• Page Start: 129
• Page End: 134
• Publication Date: 2021-07
• Subjects: Dat'AIDS cohort -- New HIV diagnoses -- HIV epidemiology -- Treatment as prevention -- 90–90–90 target -- UNAIDS -- HIV -- Antiretroviral therapy -- TasP -- Cascade of care -- PrEP; Public health -- Periodicals; Public health -- Periodicals; Electronic journals; 362.1
• DOI: 10.1016/j.puhe.2021.05.027
• Languages: English
• ISSNs: 0033-3506

Abstract

Abstract: Objectives: As trends in new HIV diagnoses represent a measure of the HIV epidemic, we conducted a 6-year longitudinal study to evaluate the change in rates of new HIV diagnosis, stratified by birthplace, HIV risk groups and CD4 cell count at diagnosis in a large French multicentre cohort. Study design: We performed a retrospective cohort study using data from the mainland French Dat'AIDS cohort. Methods: Data were obtained for subjects with a new HIV diagnosis date between 2013 and 2018. HIV diagnosis date was defined as the date of the first known positive HIV serology. Results: Between 2013 and 2018, a total of 68, 376 people living with HIV (PLHIV) were followed in the Dat'AIDS cohort; 9543 persons were newly diagnosed with HIV. The annual number of new HIV diagnoses decreased from 1856 in 2013, to 1149 in 2018 (−38.1%), P = 0.01; it was more pronounced among subjects born in France, from 858 to 484 (−43.6%), P < 0.01, than in those born abroad (−23.8%, from 821 to 626, P = 0.13). Among subjects born in France, the decrease over the period was −46.7% among men who have sex with men (MSM), −43.5% for heterosexual women and −33.3% for heterosexual men. Conclusion: Our findings show changes in HIV epidemiology in PLHIV born in France, with a decline around 40% in new HIV diagnoses, and a more pronounced decrease among MSM and heterosexual women. Our results support the long-term effectiveness of the antiretroviral therapy as a prevention strategy among the various tools for HIV prevention.