A Clinician's Guide to Topical Retinoids. Issue 1 (January 2022)

• Record Type: Journal Article
• Authors: Motamedi, Melika; Chehade, Ahmad; Sanghera, Ravina; Grewal, Parbeer
• Is Part Of: Journal of cutaneous medicine and surgery. Volume 26:Issue 1(2022)
• Page Start: 71
• Page End: 78
• Publication Date: 2022-01
• Subjects: acne -- keratinization -- retinoid; Dermatology -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; Skin -- Surgery -- Periodicals; Dermatology -- Canada -- Periodicals; Skin -- Diseases -- Treatment -- Canada -- Periodicals; Skin -- Surgery -- Canada -- Periodicals; 616.5005
• DOI: 10.1177/12034754211035091
• Languages: English
• ISSNs: 1203-4754

Abstract

Retinoids are defined as molecules that bind to and activate retinoic acid receptors to influence the proliferation and differentiation of cells. Topical retinoids have evolved over the past several decades, being used in multiple dermatological conditions. This review aims to differentiate between synthetic and natural retinoids, discuss the pharmacology behind topical retinoids, highlight clinical applications, and categorize all the commercially available agents, including combination products. Understanding retinoid affinities for unique receptor subtypes can impact clinical decisions, resulting in optimizing treatment and enhancing patient adherence.