Anticancer, antimicrobial, and dye degradation activity of biosynthesised silver nanoparticle using Artemisia kopetdaghensis. (16th December 2020)

• Record Type: Journal Article
• Authors: Taghavizadeh Yazdi, Mohammad Ehsan; Darroudi, Majid; Amiri, Mohammad Sadegh; Hosseini, Hasan Ali; Nourbakhsh, Fahimeh; Mashreghi, Mohammad; Farjadi, Malihe; Mousavi Kouhi, Seyed Mousa; Mousavi, Seyed Hadi
• Is Part Of: Micro & nano letters. Volume 15:Number 14(2020)
• Page Start: 1046
• Page End: 1050
• Publication Date: 2020-12-16
• Subjects: toxicology -- antibacterial activity -- transmission electron microscopy -- ultraviolet spectra -- biomedical materials -- catalysis -- nanoparticles -- visible spectra -- microorganisms -- silver -- dyes -- cellular biophysics -- cancer -- X‐ray diffraction -- spectrophotometry -- liver -- nanofabrication -- nanomedicine -- Fourier transform infrared spectra; Fourier transform infrared spectra -- dye degradation activity -- green‐synthesised Ak‐AgNPs -- Artemisia kopetdaghensis -- biosynthesised silver nanoparticle -- ultraviolet‐visible spectrophotometry -- XRD -- Fourier transform infrared spectra -- Streptococcus pyogenes -- Staphylococcus epidermidis -- Escherichia coli -- Klebsiella pneumoniae -- Pseudomonas aeruginosa -- Staphylococcus aureus -- human hepatocellular cancer cell line -- HepG2 cancer cells -- methylene blue; Nanotechnology -- Periodicals; Nanostructures -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1049/mnl.2020.0387
• Languages: English
• ISSNs: 1750-0443

Abstract

Abstract : Biosynthesis of nanoparticles (NPs) is gaining attention due to the presence of functional plant macromolecules that benefit from NPs' synthesis and also due to their exceptional bioactive compounds. Artemisia kopetdaghensis extract acted as a reducing/capping agent. Characterisation of greener‐synthesised AgNPs (Ak‐AgNPs) was performed by various techniques, such as Ultraviolet (UV)−visible spectrophotometry, TEM, Fourier transform infrared, and XRD. Ak‐AgNPs indicated great bactericidal properties in terms of zone of inhibition (ZI) against all of the pathogenic bacteria (i.e. Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Streptococcus pyogenes, Staphylococcus epidermidis, and Staphylococcus aureus ). The maximum ZI of Ak‐AgNPs was 22.3 and 17.8 mm against K. pneumoniae and S. aureus, respectively. Anti‐proliferative activity of Ak‐AgNPs on human hepatocellular cancer cell line (HepG2) using the MTT test showed dosage‐dependent inhibition activity of Ak‐AgNPs against HepG2 cancer cells. Also, green‐synthesised Ak‐AgNPs showed catalytic properties under UV‐light in organic dye (methylene blue) degradation. This study revealed that the green‐synthesised AgNPs using A. kopetdaghensis shoots extract had antibacterial and catalytic activities. Also, Ak‐AgNPs had anti‐proliferative potential against human liver cancer cell lines. The green‐synthesised Ak‐AgNPs have the potential to be exploited in anti‐bacterial, anticancer, and biocatalyst technologies.