Pituitary metastasis of prostate cancer presenting as a unilateral third nerve palsy. Issue 6 (11th June 2020)

• Record Type: Journal Article
• Authors: Ahmad, Sajjad; Smeeton, Fiona; Hayhurst, Caroline; Lansdown, Andrew
• Is Part Of: BMJ case reports. Volume 13:Issue 6(2020)
• Publication Date: 2020-06-11
• Subjects: pituitary disorders -- prostate cancer -- radiotherapy; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2020-234550
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : A 60-year-old man presented with right third nerve palsy and headaches. Neuroimaging showed a pituitary lesion. There was evidence of rapid enlargement on interval scans, invasion of the cavernous sinus and displacement of the pituitary stalk. He subsequently developed anterior hypopituitarism. CT thorax, abdomen and pelvis did not show any evidence of malignancy. This was thought to be an aggressive pituitary macroadenoma but histology post-trans-sphenoidal surgery surprisingly showed metastasis from an undiagnosed prostate primary. His prostate specific antigen was raised and MRI pelvis confirmed locally advanced prostate cancer.