Familial uveal melanoma. Issue 4 (April 1988)

• Record Type: Journal Article
• Authors: Canning, C. R.; Hungerford, J.
• Is Part Of: British journal of ophthalmology. Volume 72:Issue 4(1988)
• Page Start: 241
• Page End: 243
• Publication Date: 1988-04
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.72.4.241
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : The cause of uveal melanoma is unknown. In a few cases, however, factors are found in association with the disease which may play some part in the aetiology. One such factor is inheritance. Twelve families have been reported with adequate documentation during the last century in which two or more members have had uveal melanomas. At least some of these may be the result of an inherited disorder. On available data inheritance is most likely autosomal dominant with partial expressivity or incomplete penetrance. This report describes two more families each of which have two members with uveal melanomas.