Manipulative and inherent errors in anti-D quantitation using the AutoAnalyzer. Issue 3 (March 1972)

• Record Type: Journal Article
• Authors: Gunson, H. H.; Phillips, P. K.; Stratton, F.
• Is Part Of: Journal of clinical pathology. Volume 25:Issue 3(1972)
• Page Start: 198
• Page End: 205
• Publication Date: 1972-03
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.25.3.198
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : The limits of accuracy for the quantitation of anti-D using the AutoAnalyzer have been reduced from ± 26% with manually prepared dilutions to ± 14% using an automatic pipette, as expressed by the 95% confidence limits. The error inherent in the AutoAnalyzer was estimated to contribute ± 10% to the overall error. Problems associated with the reproducibility of this method for anti-D quantitation have been investigated, namely, the effect of the age of a given test cell, the use of different test cells, loss of sensitivity of the machine over a given day, and the reproducibility of results obtained at different positions on the standard graph.