Antenatal detection of grossly distended bladder owing to absence of the urethra in a fetus with trisomy 18. Issue 2 (April 1983)

• Record Type: Journal Article
• Authors: Nevin, N C; Nevin, J; Dunlop, J M; Gray, M
• Is Part Of: Journal of medical genetics. Volume 20:Issue 2(1983)
• Page Start: 132
• Page End: 133
• Publication Date: 1983-04
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.20.2.132
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : An ultrasonic examination revealed a grossly distended fetal abdomen. Amniocentesis at 19 weeks' gestation showed raised amniotic fluid alphafetoprotein, a second band of specific acetylcholinesterase, and a fetal karyotype 47, XY, +18. The pregnancy was terminated and the necropsy examination showed absence of the urethra, grossly distended bladder, hydroureters, and congenital heart anomalies.