Bubble formation occurs in insulin pumps in response to changes in ambient temperature and atmospheric pressure but not as a result of vibration. Issue 1 (17th August 2014)

• Record Type: Journal Article
• Authors: Lopez, Prudence E; King, Bruce R; Goss, Peter W; Chockalingam, Ganesh
• Is Part Of: BMJ open diabetes research and care. Volume 2:Issue 1(2014)
• Publication Date: 2014-08-17
• Subjects: Insulin Pump Therapy -- Parenting Stress -- Pediatric Diabetes; Diabetes -- Periodicals; 616.462005
• DOI: 10.1136/bmjdrc-2014-000036
• Languages: English
• ISSNs: 2052-4897

Abstract

Abstract : Introduction: Bubble formation in insulin pump giving sets is a common problem. We studied change in temperature, change in atmospheric pressure, and vibration as potential mechanisms of bubble formation. Methods: 5 Animas 2020 pumps with 2 mL cartridges and Inset II infusion systems, 5 Medtronic Paradigm pumps with 1.8 mL cartridge and Quickset and 3 Roche Accu-chek pumps with 3.15 mL cartridges were used. Temperature study: insulin pumps were exposed to a temperature change from 4°C to 37°C. Pressure study: insulin pumps were taken to an altitude of 300 m. Vibration study: insulin pumps were vigorously shaken. All were observed for bubble formation. Results: Bubble formation was observed with changes in temperature and atmospheric pressure. Bubble formation did not occur with vibration. Discussion: Changes in insulin temperature and atmospheric pressure are common and may result in bubble formation. Vibration may distribute bubbles but does not cause bubble formation.