Peritoneal Tuberculosis: A Retrospective Review of 20 Cases and Comparison With Primary Peritoneal Carcinoma. Issue 5 (1st June 2010)

• Record Type: Journal Article
• Authors: Choi, Chel Hun; Kim, Chul-Jung; Lee, Yoo-Young; Kim, Joo Sun; Song, Taejong; Park, Hwang-Shin; Kim, Min Kyu; Kim, Tae-Joong; Lee, Jeong-Won; Lee, Je-Ho; Bae, Duk-Soo; Kim, Byoung-Gie
• Is Part Of: International journal of gynecological cancer. Volume 20:Issue 5(2010)
• Page Start: 798
• Page End: 803
• Publication Date: 2010-06-01
• Subjects: Peritoneal tuberculosis -- Primary peritoneal cancer; Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1111/IGC.0b013e3181e23c8f
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Introduction: To evaluate the clinical features of peritoneal tuberculosis (TB) and to compare them with those of primary peritoneal carcinoma (PPC). Methods: We conducted a retrospective review of women with peritoneal TB who were managed at Samsung Medical Center from January 1996 to October 2006. As a control sample, patients with a diagnosis of PPC during the same period were also selected for comparison. Results: During the study period, we identified 20 female patients with peritoneal TB. The median age was 39 years (range, 23-69 years), and the median cancer antigen 125 (CA-125) level was 448 U/mL (range, 32-1725 U/mL). Seventeen patients with PPC whom we examined were older, with a median age of 63 years (range, 50-73 years); their median CA-125 level was higher at 1848 U/mL (range, 42-14, 380 U/mL). Compared with those of PPC, the radiologic findings of peritoneal TB indicated less severe involvement of the omentum and the mesentery ( P = 0.03). Among the 20 patients who underwent operations, 6 (30%) underwent exploratory laparotomy; 12 (60%), diagnostic laparoscopy; and 2 (10%), laparoscopy converted to laparotomy because of severe adhesion. Frozen tissue sections revealed chronic granulomatous tissue reaction in 15 (83.3%) of 18 women with peritoneal TB. Conclusions: Maintaining a high index of suspicion is very important for the successful treatment of peritoneal TB, especially in developing countries. Age, CA-125 level, and omental involvement as identified by computed tomography may be helpful for the differential diagnosis of peritoneal TB and PPC.