A complex double translocation involving four chromosomes and five breakpoints in a child with mild mental retardation. Issue 5 (October 1983)

• Record Type: Journal Article
• Authors: Couzin, D A; Watt, J L; Auchterlonie, I A
• Is Part Of: Journal of medical genetics. Volume 20:Issue 5(1983)
• Page Start: 389
• Page End: 392
• Publication Date: 1983-10
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.20.5.389
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : A 6-year-old boy with speech delay and mild mental retardation (IQ 82) was found to have a complex double translocation involving four chromosomes and a total of five breakpoints, two being on the same arm. This resulted in the karyotype 46, XY, t(2;4;7)(7;8)(q14;q31;q11q22;q13). As far as the authors are aware this is the first time that such a complex double translocation has been reported. Both parents had normal karyotypes.