Pathological investigation and viral antigen distribution of emerging African swine fever in Vietnam. Issue 4 (7th October 2020)

• Record Type: Journal Article
• Authors: Izzati, Uda Zahli; Inanaga, Minori; Hoa, Nguyen Thi; Nueangphuet, Phawut; Myint, Ohnmar; Truong, Quang Lam; Lan, Nguyen Thi; Norimine, Junzo; Hirai, Takuya; Yamaguchi, Ryoji
• Is Part Of: Transboundary and emerging diseases. Volume 68:Issue 4(2021)
• Page Start: 2039
• Page End: 2050
• Publication Date: 2020-10-07
• Subjects: Asfarviridae -- domestic pig -- histopathology -- immunohistochemistry -- natural outbreak; Veterinary medicine -- Periodicals; 636.089
• DOI: 10.1111/tbed.13851
• Languages: English
• ISSNs: 1865-1674

Abstract

Abstract: African swine fever (ASF) is emerging in Vietnam and poses a continuing severe threat to the swine industry. A histopathological study of clinical samples collected during the May to July 2019 outbreak of ASF was performed to determine the characteristic lesions. We analysed samples from eight ASFV‐infected farms. Histopathological results revealed the characteristic lesions of the acute to the subacute clinical form of ASF. Immunohistochemical results showed ASFV viral antigen distribution in mononuclear cells/macrophage in various organs, hepatocytes and renal tubular epithelium. Molecular analysis of partial capsid protein 72 gene revealed that ASFV strain from the eight separate outbreaks belonged to genotype II.