Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates. Issue 8 (29th June 2021)

• Record Type: Journal Article
• Authors: Smyth, Robert; Sloan, John Mark; Burks, Eric; Hawkins, Finn
• Is Part Of: Respirology case reports. Volume 9:Issue 8(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-06-29
• Subjects: Extra‐nodal lymphoma -- MALToma -- marginal zone -- pulmonary lymphoma -- rare lung tumour; Respiratory organs -- Diseases -- Periodicals; 616.2005
• DOI: 10.1002/rcr2.806
• Languages: English
• ISSNs: 2051-3380

Abstract

Abstract: Primary pulmonary extra‐nodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma), also known as bronchus‐associated lymphoid tissue (BALT lymphoma), is the most common primary pulmonary lymphoma but is rare (<1%) among all non‐Hodgkin lymphomas and among pulmonary neoplasms in general. We herein report the case of a 59‐year‐old male who presented with stable exertional dyspnoea and persistent lung infiltrates who was referred to our hospital for further assessment. A computed tomography (CT)‐guided core biopsy was performed showing a dense lymphoid infiltrate, with further testing revealing the diagnosis of pulmonary MALT lymphoma. This uncommon lung tumour is usually seen in older adults and typically associated with a relatively indolent course. Rituximab, an anti‐CD20 antibody, has been shown to be effective in up to 70% of cases. Abstract : A middle‐aged male presents with dyspnoea and multifocal consolidations. Biopsy shows pulmonary MALT lymphoma, a rare lung tumour.