IgG4-related disease presenting as a paraneoplastic syndrome: report of two cases and literature review. (3rd April 2021)

• Record Type: Journal Article
• Authors: Akahoshi, Mitsuteru; Arinobu, Yojiro; Kashiwado, Yusuke; Omoto, Aya; Ayano, Masahiro; Mitoma, Hiroki; Kimoto, Yasutaka; Ono, Nobuyuki; Horiuchi, Takahiko; Niiro, Hiroaki
• Is Part Of: Modern rheumatology case reports. Volume 5:Number 2(2021)
• Page Start: 371
• Page End: 376
• Publication Date: 2021-04-03
• Subjects: IgG4-related disease -- malignancy -- cancer -- paraneoplastic syndrome -- inflammatory carcinogenesis; Rheumatology -- Periodicals; 616.723005
• DOI: 10.1080/24725625.2021.1896096
• Languages: English
• ISSNs: 2472-5625

Abstract

Abstract: An association between immunoglobulin G4-related disease (IgG4-RD) and malignancy has been suggested. We report two cases of IgG4-RD with suspected paraneoplastic syndrome. In both patients, malignancy was observed immediately after diagnosis of IgG4-RD, and surgical resection resulted in spontaneous regression of IgG4-RD. We review the reports on IgG4-RD associated with malignancy, including these two cases, and discuss their relevance.