Ruthenium-catalyzed C–H amination of aroylsilanes. Issue 28 (2nd July 2021)

• Record Type: Journal Article
• Authors: Yu, Feifei; Shen, Wenzhou; Sun, Yaling; Liao, Yilei; Jin, Shuqi; Lu, Xiunan; He, Rui; Zhong, Liangjun; Zhong, Guofu; Zhang, Jian
• Is Part Of: Organic & biomolecular chemistry. Volume 19:Issue 28(2021)
• Page Start: 6313
• Page End: 6321
• Publication Date: 2021-07-02
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d1ob00935d
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : Acylsilane represents one valuable synthon in synthetic chemistry. We report on ruthenium(ii )-catalyzed ortho -C–H amination of aroylsilanes to provide facile access to synthetically useful imidobenzoylsilanes and tosyl-amidobenzoylsilanes. Abstract : Acylsilane represents a valuable synthon in synthetic chemistry. We report on ruthenium(ii )-catalyzed ortho -C–H amination of aroylsilanes to provide facile access to synthetically useful imidobenzoylsilanes and tosyl-amidobenzoylsilanes. The protocols, with broad substrate scope and excellent functional group tolerance, are enabled with the weak chelation-assistance of acylsilane via C–H cyclometallation.