Sedation, narcotic and neuromuscular blockade in mechanically ventilated patients with COVID-19. (August 2021)

• Record Type: Journal Article
• Authors: Rizvi, Ghazi; Yamane, David; Davison, Danielle; Williams, Jeffrey; Heinz, Eric R.
• Is Part Of: Trends in anaesthesia and critical care. Volume 39(2021)
• Page Start: 19
• Page End: 20
• Publication Date: 2021-08
• Subjects: COVID-19 -- Sedation -- Analgesia -- Neuromuscular blockade -- Mechanical ventilation; Anesthesia -- Periodicals; Critical care medicine -- Periodicals; Anesthesia in traumatology -- Periodicals; Anesthesia -- Case studies -- Periodicals; 617.9605
• DOI: 10.1016/j.tacc.2021.06.001
• Languages: English
• ISSNs: 2210-8440

Abstract

Abstract: Objective: To describe the sedation, narcotic and neuromuscular blockade usage in ventilated patients with COVID-19 pneumonia. Design: Single-Center Retrospective Review. Setting: George Washington University Hospital in Washington, D.C. Patients: 62 patients with COVID-19 respiratory failure requiring mechanical ventilation admitted from March 2020 to June 2020. Intervention: None. Measurements and main results: Patients with COVID-19 respiratory failure required multiple sedative/narcotic infusions to achieve sedation requirements and at doses that were significantly more when compared to a general medical-surgical ICU population (represented by the MIND-USA cohort). The most common infusions were Dexmedetomadine and Propofol. Approximately 17% of our patients required a neuromuscular blockade infusion as well. Prior to intubation, narcotic utilization was stable and low. Conclusion: Patients with COVID-19 respiratory failure requiring mechanical ventilation have higher sedation and narcotic requirements than general ICU patients.