A new method using xenogeneicacellular dermal matrix in the reconstruction of lacrimal drainage. Issue 11 (11th June 2014)

• Record Type: Journal Article
• Authors: Chen, Li; Gong, Bo; Wu, Zhengzheng; Jetton, Jacquelyn; Chen, Rong; Qu, Chao
• Is Part Of: British journal of ophthalmology. Volume 98:Issue 11(2014)
• Page Start: 1583
• Page End: 1587
• Publication Date: 2014-06-11
• Subjects: Lacrimal duct -- Graft; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjophthalmol-2014-304932
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Aims: To prospectively evaluate the reliability and efficacy of a new treatment for the reconstruction of the lacrimal duct using a new histo-engineered material, xenogeneic (bovine) acellular dermal matrix. Method: Five patients (five eyes) with partial or total absence of the lacrimal duct were included in the study. Four patients (four eyes) suffered from traumatic injuries to the lacrimal duct and one patient (one eye) had congenital absence of the lacrimal drainage system. A pedal graft of conjunctiva was taken from the fornix area and rolled into a tube structure after being attached to the acellular dermal matrix. Results: The average duration of follow-up for the patients was 7.2 months (ranging from 6 to 12 months). After surgery, the new duct in the nasal cavity could be observed above the middle turbinate by nasal endoscopy. Patency was confirmed by pressing in the area of the lacrimal sac and visualising air bubbles in the nasal cavity. Additionally, the meatus above the middle turbinate of the nasal cavity was stained and visualised after patients underwent Jones dye test 1 (JDT1). Five tear ducts proved to be effective through irrigation testing and epiphora symptoms were alleviated in all cases. Conclusions: The newly reconstructed lacrimal duct, formed by the shift of autogenous conjunctival petal and the attachment of acellular dermal matrix, was successful in all five cases and suggests a new solution for the complex lacrimal duct lesion and congenital anomalies of the lacrimal duct.