Pure testicular carcinoid associated with intratubular germ cell neoplasia. Issue 12 (25th November 2005)

• Record Type: Journal Article
• Authors: Merino, J; Zuluaga, A; Gutierrez-Tejero, F; del Mar Serrano, M; Ciani, S; Nogales, F F
• Is Part Of: Journal of clinical pathology. Volume 58:Issue 12(2005)
• Page Start: 1331
• Page End: 1333
• Publication Date: 2005-11-25
• Subjects: ITGCN, intratubular germ cell neoplasia -- PLAP, placental-like alkaline phosphatase; testis -- carcinoid -- intratubular germ cell neoplasia -- carcinoma in situ; Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.2004.022541
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : This case report describes for the first time a case of pure testicular carcinoid preaortic lymph node metastases in a 25 year old patient with carcinoid syndrome. The simultaneous occurrence of intratubular germ cell neoplasia in the surrounding testicular tissue was identified by OCT4 and placental-like alkaline phosphatase positivity. This confirmed that the tumour had a germ cell origin in the testis, rather than being a metastasis from an extragenital carcinoid.