No effect of intramuscular gold therapy on serological parameters of Helicobacter pylori infection in patients with rheumatoid arthritis: a 12 month prospective study. Issue 6 (June 1994)

• Record Type: Journal Article
• Authors: ten Wolde, S; Janssen, M; van Duijn, W; Lamers, C B; Hermans, J; Dijkmans, B A
• Is Part Of: Annals of the rheumatic diseases. Volume 53:Issue 6(1994)
• Page Start: 400
• Page End: 402
• Publication Date: 1994-06
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.53.6.400
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : OBJECTIVES--To assess prospectively the influence of intramuscular gold therapy on Helicobacter pylori serology in patients with rheumatoid arthritis (RA). METHODS--Fifty patients with RA were started on intramuscular gold or chloroquine, as the control group and were followed serologically for H pylori infection for 12 months. RESULTS--Twelve patients treated with gold and eight control patients treated with chloroquine, all with serological evidence for H pylori infection, showed no significant decline of IgA and IgG anti-H pylori antibody levels or serum pepsinogen A and C levels. Total serum IgA and IgG levels declined significantly during gold therapy, while they remained unchanged during chloroquine therapy. CONCLUSIONS--Intramuscular gold therapy in patients with RA does not influence the serological parameters of H pylori infection.