Maternal diabetes mellitus and congenital malformation. Survey of 205 cases. Issue 12 (December 1976)

• Record Type: Journal Article
• Authors: Day, R E; Insley, J
• Is Part Of: Archives of disease in childhood. Volume 51:Issue 12(1976)
• Page Start: 935
• Page End: 938
• Publication Date: 1976-12
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.51.12.935
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Twenty-five out of 205 (i.e. 12%) babies born to diabetic mothers in the Birmingham Maternity Hospital in the period 1969-1974 were malformed as against 6% in a control group. The incidence was highest in the group where mothers were on insulin at the time of conception (17 out of 117, i.e. 15%). No correlation was observed between major malformation in this group and age of onset or duration of the diabetes, progressive vascular complications, maternal age, or parity. Cardiovascular malformations were over-represented.