The risk of antimalarials in patients with renal failure. Issue 986 (5th December 2007)

• Record Type: Journal Article
• Authors: Thorogood, N; Atwal, S; Mills, W; Jenner, M; Lewis, D A; Cavenagh, J D; Agrawal, S G
• Is Part Of: Postgraduate medical journal. Volume 83:Issue 986(2007)
• Page Start: 8
• Page End: 8
• Publication Date: 2007-12-05
• Subjects: antimalarials -- end stage renal failure -- exfoliative dermatitis -- megaloblastic anaemia -- pancytopenia; Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.2007.063735
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : We present here a patient with end stage renal failure who received two weeks antimalarial prophylaxis at full dose leading to life threatening toxicity with severe acute megaloblastic anaemia, symptomatic pancytopenia and exfoliative dermatitis. Prompt recognition and treatment can rapidly reverse these fatal effects but more importantly, education of patients before travel is imperative in preventing such events.