Risk factors for further sick leave among Japanese workers returning to work after an episode of major depressive disorder: a prospective follow-up study over 1 year. Issue 9 (11th September 2019)

• Record Type: Journal Article
• Authors: Hori, Hikaru; Katsuki, Asuka; Atake, Kiyokazu; Yoshimura, Reiji; Nakamura, Jun; Baune, Bernhard T
• Is Part Of: BMJ open. Volume 9:Issue 9(2019)
• Publication Date: 2019-09-11
• Subjects: Major depressive disorder -- cognitive function -- social functioning -- sick leave -- return to work; Medicine -- Research -- Periodicals; 610.72
• DOI: 10.1136/bmjopen-2019-029705
• Languages: English
• ISSNs: 2044-6055

Abstract

Abstract : Objectives: We aimed to investigate the risk factors for further sick leave episodes among Japanese workers returning to work after time off with a major depressive disorder. Design: A prospective study with 1 year of follow-up. Participants: We recruited 103 workers who had returned to work after taking sick leave with a major depressive disorder. Adjusted HRs with 95% CIs were calculated using Cox proportional hazard models to examine the risk of further sick leave. Results: In the adjusted analysis, we show that Social Adaptation Self-evaluation Scale scores (HR 0.95; p=0.019), 3-back correct response rate (N-back test) (HR 0.97; p<0.001) and benzodiazepine dosage (diazepam equivalent) (HR1.07; p=0.014) were associated with further episodes of sick leave. Conclusions: Poorer social and cognitive functioning, together with higher diazepam dosages, were associated with an increased likelihood of additional sick leave.