Antibodies to lens antigens in cataract and after cataract surgery. Issue 1 (January 1981)

• Record Type: Journal Article
• Authors: Nissen, S. H.; Andersen, P.; Andersen, H. M.
• Is Part Of: British journal of ophthalmology. Volume 65:Issue 1(1981)
• Page Start: 63
• Page End: 66
• Publication Date: 1981-01
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.65.1.63
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : By means of an enzyme-linked immunosorbent assay (ELISA) antibodies to whole lens homogenate were found in 50.0% of 38 patients with senile cataract and in 57.3% of 75 controls. The antibody titres were in the range of 10-160 in both groups. IgG antibodies occurred in 44.7% of patients and in 45.3% of controls, whereas IgM antibodies were found in 21.1% of the patients and in 40.0% of the controls (not significant). Postoperative uveitis occurred in 5 (31.6%) of 19 patients, who had antibodies in serum prior to the operation and in only 2 (10.5%) of 19 antibody-negative patients (P = 0.10).