Serum concentrations of two biochemical markers of brain tissue damage S-100B and neurone specific enolase are increased in elite female soccer players after a competitive game. Issue 4 (23rd March 2006)

• Record Type: Journal Article
• Authors: Stålnacke, B-M; Ohlsson, A; Tegner, Y; Sojka, P
• Is Part Of: British journal of sports medicine. Volume 40:Issue 4(2006)
• Page Start: 313
• Page End: 316
• Publication Date: 2006-03-23
• Subjects: MTBI, mild traumatic brain injury -- NSE, neurone specific enolase; brain injury -- biochemical markers -- concussion -- soccer; Sports medicine -- Periodicals; 617.1027
• DOI: 10.1136/bjsm.2005.021584
• Languages: English
• ISSNs: 0306-3674

Abstract

Abstract : Background: It is a matter of debate whether or not ordinary heading of the ball in soccer causes injury to brain tissue. Objective: To analyse concentrations of the biochemical markers of brain tissue damage S-100B and neurone specific enolase (NSE) in serum of female elite soccer players in association with a competitive game. Methods: Venous blood samples were obtained from 44 female soccer players before and after a competitive game for analysis. The number of headers and trauma events (falls, collisions, etc) was assessed from videotape recordings for each player. Results: Concentrations of both brain damage markers were increased after the game (S-100B, 0.18 (0.11) v 0.11 (0.05) μg/l (p = 0.000); NSE, 10.14 (1.74) v 9.05 (1.59) μg/l (p = 0.001)). There was a significant correlation between changes in S-100B concentrations and both the number of headers ( r = 0.430, p = 0.004) and the number of other trauma events ( r = 0.517, p<0.001). Conclusion: The concentrations of both S-100B and NSE were increased by game associated activities and events. The increases in S-100B concentration were significantly related to the number of headers and other trauma events, which indicates that both these factors may have contributed to these increases.