Preretinopic changes in the colour vision of juvenile diabetics. Issue 1 (1st January 1999)

• Record Type: Journal Article
• Authors: Kurtenbach, Anne; Schiefer, Ulrich; Neu, Andreas; Zrenner, Eberhart
• Is Part Of: British journal of ophthalmology. Volume 83:Issue 1(1999)
• Page Start: 43
• Page End: 46
• Publication Date: 1999-01-01
• Subjects: anomaloscope -- blood glucose -- colour vision -- diabetes; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.83.1.43
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : AIMS: To examine the colour vision of juvenile patients suffering from diabetes mellitus without retinopathy in relation to metabolic and ophthalmic state. METHODS: Metameric matches, both Rayleigh (red/green) and Moreland (blue/green) were used to test the colour vision yearly of 10 juvenile patients. The patients were monitored over 4 years, and during the final year, their blood glucose level was determined directly after testing colour vision. An ophthalmic examination was performed on the day of colour vision testing and blood and urine were analysed regularly throughout the 4 years. Their results are compared with an aged matched control group of 20 subjects, seven of whom were retested after 9–16 months. RESULTS: After 4 years, the colour vision results show an enlarged matching range for the Moreland match, as well as a smaller increase in the matching range for the Rayleigh match. No significant correlation was found between blood glucose at the time of testing and any of the variables measured. CONCLUSION: The pattern of colour vision deficits in metameric matching shown by juvenile diabetics is consistent with post-receptoral alterations of the inner retina, at this preretinopic stage of disease. Duration of diabetes is correlated with both colour vision changes and morphological alteration of the retina.