ALK positive inflammatory myofibroblastic tumour of the pineal region. Issue 9 (26th August 2005)

• Record Type: Journal Article
• Authors: Clarke, A J; Jacques, T S; Galloway, M J; Thom, M; Kitchen, N D; Plant, G T
• Is Part Of: Journal of clinical pathology. Volume 58:Issue 9(2005)
• Page Start: 981
• Page End: 983
• Publication Date: 2005-08-26
• Subjects: ALK, anaplastic lymphoma kinase -- IMT, anaplastic lymphoma kinase; inflammatory myofibroblastic tumour -- inflammatory pseudotumour -- anaplastic lymphoma kinase -- anaplastic lymphoma kinase; Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.2004.022947
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : Inflammatory myofibroblastic tumours (IMTs) are an uncommon spindle cell neoplasm with a dense inflammatory infiltrate, usually encountered in children. IMTs of the central nervous system are extremely rare. This report describes the case of an IMT in a 61 year old man, in the pineal region. The tumour was completely excised, and immunohistochemistry demonstrated anaplastic lymphoma kinase 1 expression. There was no tumour recurrence during 18 months of follow up. Our case extends both the age range and sites of occurrence of this rare tumour.