Regression of gastric T cell lymphoma with eradication ofHelicobacter pylori. Issue 2 (1st February 2001)

• Record Type: Journal Article
• Authors: Bariol, C; Field, A; Vickers, C R; Ward, R
• Is Part Of: Gut. Volume 48:Issue 2(2001)
• Page Start: 269
• Page End: 271
• Publication Date: 2001-02-01
• Subjects: Helicobacter pylori -- T cell lymphoma; Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.48.2.269
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Helicobacter pylori is thought to be important in the pathogenesis of chronic active gastritis, peptic ulceration, gastric adenocarcinoma, and gastric B cell lymphoma of mucosa associated lymphoid tissue. The mechanism of evolution from chronic gastritis to monoclonal B cell proliferation is not known but is thought to be dependent on antigen specific T cells to H pylori and its products. Here, we report a case of gastric T cell lymphoma associated with chronic H pylori gastritis which regressed with eradication of the organism. This is the first report of a gastric T cell lymphoma regressing with H pylori eradication, and suggests a causal link between primary gastric T cell lymphoma and this organism.