High mortality with High false negative rate: COVID-19 infection in patients with hematologic malignancies. (July 2021)

• Record Type: Journal Article
• Authors: Niu, Alex; Ning, Bo; Socola, Francisco; Safah, Hana; Reynolds, Tim; Ibrahim, Moayed; Safa, Firas; Alfonso, Tina; Luk, Alfred; Mushatt, David M.; Hu, Tony; Saba, Nakhle S.
• Is Part Of: Leukemia research. Volume 106(2021)
• Publication Date: 2021-07
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2021.106582
• Languages: English
• ISSNs: 0145-2126

Abstract

Highlights: Blood cancers are associated with high rates of SARS-CoV-2 RT-PCR false negativity. False negative RT-PCR COVID-19 results can be detected by CRISPR-based assays. COVID-19 in patients with hematologic malignancies confers worse survival. Lympho-depleting chemotherapy may result in higher COVID-19 mortality.