Recalcitrant lymphocytoma cutis successfully treated with mycophenolate mofetil. (June 2021)

• Record Type: Journal Article
• Authors: Mahmood, Farhan; Teo, Iris YH; Kirchhof, Mark G
• Is Part Of: SAGE open medical case reports. Volume 9(2021)
• Publication Date: 2021-06
• Subjects: Lymphocytoma cutis -- cutaneous lymphoid hyperplasia -- mycophenolate mofetil -- immunosuppressant; Clinical medicine -- Case studies -- Periodicals; 616.09
• DOI: 10.1177/2050313X211025104
• Languages: English
• ISSNs: 2050-313X

Abstract

Lymphocytoma cutis reflects an exaggerated local immunologic reaction to a stimulus presenting on the head, neck, or upper extremities as a firm 1–3 cm erythematous and/or violaceous plaque or nodule. However, lymphocytoma cutis may be difficult to treat due to the variety of causative agents and the lack of reported successful treatments and outcomes. Here, we present a case of 68-year-old female with recalcitrant lymphocytoma cutis resistant to other first-line therapies including tacrolimus ointment and steroids. The red plaque on the patient's left cheek was eventually treated with mycophenolate mofetil. Mycophenolate mofetil was an accessible and effective therapeutic option to treat lymphocytoma cutis with minimal side effects.