COVID-19 Induced Miller Fisher Syndrome Presenting With Autonomic Dysfunction: A Unique Case Report and Review of Literature. (January 2022)

• Record Type: Journal Article
• Authors: Biswas, Subhrajyoti; Ghosh, Ritwik; Mandal, Arpan; Pandit, Alak; Roy, Dipayan; Sengupta, Samya; De, Kaustav; Swaika, Bikash Chandra; Benito-León, Julián
• Is Part Of: Neurohospitalist. Volume 12:Number 1(2022)
• Page Start: 111
• Page End: 116
• Publication Date: 2022-01
• Subjects: Autonomic dysfunction -- COVID-19 -- Miller Fisher syndrome (MFS) -- SARS-CoV-2; Nervous system -- Diseases -- Periodicals; Neurology -- Periodicals; 616.8
• DOI: 10.1177/19418744211016709
• Languages: English
• ISSNs: 1941-8744

Abstract

A plethora of neurological manifestations are associated with the 2019 coronavirus infectious disease (COVID-19). We hereby report the first case of a patient infected with SARS-CoV-2 who acutely presented with autonomic dysfunction preceding the onset of complete clinical picture of Miller Fisher syndrome. She was finally diagnosed to be a case of anti-ganglioside antibody positive post-COVID-19 Miller Fisher syndrome with dysautonomia and treated with intravenous immunoglobulin with an excellent response. We also discuss the plausible pathogenic mechanisms of COVID-19 induced Miller Fisher syndrome and furnish a review of the post-COVID-19 Miller Fisher syndrome cases reported.