Surgical treatment of liver and kidney metastasis from an adenoid cystic carcinoma of the submandibular gland: case report. Issue 6 (December 2021)

• Record Type: Journal Article
• Authors: Ferrari, Cecilia; Franceschi, Angelo; Percivale, Andrea; Griseri, Guido
• Is Part Of: Tumori. Volume 107:Issue 6(2021)
• Page Start: NP87
• Page End: NP90
• Publication Date: 2021-12
• Subjects: Hepatopancreatobiliary surgery -- oncologic surgery -- liver metastases -- ACC; Cancer -- Periodicals; 616.994
• DOI: 10.1177/03008916211021664
• Languages: English
• ISSNs: 0300-8916

Abstract

Introduction: Adenoid cystic carcinomas (ACCs) account for 10% of all malignant salivary tumours. They are slow-growing but locally aggressive. Reports of liver and renal metastases are rare. Case description: A 58-year-old woman who had undergone resection of a left submandibular ACC in 1995 was referred to our centre for follow-up in 2018. A computed tomography scan revealed two lesions: one on segment six of the liver and the other on a kidney. A hepatic wedge resection and right nephrectomy were performed. The postoperative course was uneventful. At 2-year follow-up, the patient was alive and well with no evidence of disease. Conclusion: Management of ACC is a therapeutic challenge because of its tendency for distant metastases. The literature recommends regular follow-up imaging and radical surgical treatment but specific guidelines for the approach to recurrence are lacking.