Bioactive refinement for endosaccular treatment of intracranial aneurysms. Issue 6 (December 2021)

• Record Type: Journal Article
• Authors: Szatmary, Zoltan; Mounier, Jérémy; Janot, Kevin; Cortese, Jonathan; Couquet, Claude; Chaubet, Frédéric; Kadirvel, Ramanathan; Bardet, Sylvia M; Mounayer, Charbel; Rouchaud, Aymeric
• Is Part Of: Neuroradiology journal. Volume 34:Issue 6(2021)
• Page Start: 534
• Page End: 541
• Publication Date: 2021-12
• Subjects: Intracranial aneurysm -- healing -- bioactive -- review -- coils -- biological optimisation -- endovascular treatment; Nervous system -- Radiography -- Periodicals; Neuroradiography -- Periodicals; Electronic journals; 616.804757
• DOI: 10.1177/19714009211024631
• Languages: English
• ISSNs: 1971-4009

Abstract

Endovascular treatment is the first-line therapy for most intracranial aneurysms; however, recanalisation remains a major limitation. Developments in bioengineering and material science have led to a novel generation of coil technologies for aneurysm embolisation that address clinical challenges of aneurysm recurrence. This review presents an overview of modified surface coil technologies and summarises the state of the art regarding their efficacy and limitations based on experimental and clinical results. We also present potential perspectives to develop biologically optimised devices.