Initial Experiences with the MitraClip G4: Review of the Novel Device Features. Issue 5 (September 2021)

• Record Type: Journal Article
• Authors: Ives, Christopher W.; Prejean, Shane P.; Vardas, Panos N.; Von Mering, Gregory; Ahmed, Mustafa I.
• Is Part Of: Innovations. Volume 16:Issue 5(2021)
• Page Start: 448
• Page End: 455
• Publication Date: 2021-09
• Subjects: mitral regurgitation -- percutaneous edge-to-edge mitral valve repair -- MitraClip -- controlled gripper actuation; Cardiovascular system -- Surgery -- Periodicals; Heart -- Surgery -- Periodicals; Blood-vessels -- Surgery -- Periodicals; Chest -- Surgery -- Periodicals; Thoracic Surgical Procedures -- methods -- Periodicals; Vascular Surgical Procedures -- methods -- Periodicals; Thorax -- Chirurgie -- Méthodologie -- Périodiques; Vaisseaux sanguins -- Chirurgie -- Méthodologie -- Périodiques; Blood-vessels -- Surgery; Chest -- Surgery; Periodicals; 617.41
• DOI: 10.1177/15569845211030862
• Languages: English
• ISSNs: 1556-9845

Abstract

Objective: Percutaneous edge-to-edge mitral valve repair is an evolving procedure with increasing indications for use. The MitraClip™ G4 is the newest device with 4 device options, each with distinct characteristics. While the NTR and XTR clips have been in use, the G4 adds 2 new wider clips with additional features, the NTW and XTW. Methods: We reviewed 26 cases employing the MitraClip G4 at our institution from November 2019 to March 2020. Results: The NTR, XTR, NTW, and XTW clips were used in 3 (11.5%), 0 (0.0%), 16 (61.5%), and 11 (42.3%) cases, respectively. Median mitral regurgitation grade was reduced from 4+ to 1+, though 7 (27%) cases had 2+ residual mitral regurgitation. Conclusions: The new G4 device includes simplified instructions for use, the option of a wider clip, controlled gripper actuation, and potential left atrial pressure monitoring. The newest MitraClip G4 device allows for potential improved treatment options for patients with mitral regurgitation.